Pharmaceutical intermediates are the drugs used as raw materials for the production of bulk drugs, or they can refer to a material produced during the synthesis of an API that must undergo further molecular change or processing before it becomes an API.

Pharmaceutical intermediates can be divided into antibiotic intermediates, antipyretic and analgesic intermediates, cardiovascular intermediates and anticancer intermediates according to their application fields.
How does an API differ from a pharmaceutical intermediate? 

Although APIs and intermediates are both pharmacologically active, they differ in function, composition and structure. Unlike APIs, which are usually safe and administered for therapeutic purposes after due research, intermediates may either be therapeutic, toxic or even APIs. However, APIs produced as by-products that are not officially approved, cannot be administered or used as active ingredients. Also, intermediates do not need to be approved or regulated to be utilized, unlike active ingredients that contain specialty chemical.



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